Characterization of Adhesive and Neurotoxic Components in Skin Granular Gland Secretions of Ambystoma tigrinum

Valerie K. Hamning; Heather L. Yanites; Nancy L. Peterson

doi:10.1643/0045-8511(2000)000[0856:COAANC]2.0.CO;2

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Valerie K. Hamning,¹ Heather L. Yanites,¹ Nancy L. Peterson^1,2

¹Chemistry Department, North Central College, 30 North Brainard Street, Naperville, Illinois.
². Send reprint requests to NLP. nlp@noctrl.edu

Abstract

Ambystomatid salamanders have been shown to have toxic and adhesive secretions which serve as important antipredator mechanisms. Here we show that at least one component in Ambystoma tigrinum secretion inhibits neurotransmission in slices of rat hippocampus. Further, we show that disulfide linkages in proteins are necessary for the adhesive properties of the secretion.

The American Society of Ichthyologists and Herpetologists

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Valerie K. Hamning, Heather L. Yanites, and Nancy L. Peterson "Characterization of Adhesive and Neurotoxic Components in Skin Granular Gland Secretions of Ambystoma tigrinum," Copeia 2000(3), 856-859, (1 August 2000). https://doi.org/10.1643/0045-8511(2000)000[0856:COAANC]2.0.CO;2

Accepted: 1 February 2000; Published: 1 August 2000

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